{"id":1618,"date":"2022-02-09T14:29:34","date_gmt":"2022-02-09T14:29:34","guid":{"rendered":"https:\/\/salzhauershortt.com\/?p=1618"},"modified":"2025-02-13T22:11:36","modified_gmt":"2025-02-13T22:11:36","slug":"aims-v-garland-a-disappointment-for-psilocybin-advocates-but-progressive-policy-may-still-be-on-the-horizon","status":"publish","type":"post","link":"https:\/\/salzhauershortt.com\/index.php\/2022\/02\/09\/aims-v-garland-a-disappointment-for-psilocybin-advocates-but-progressive-policy-may-still-be-on-the-horizon\/","title":{"rendered":"AIMS v. Garland: A Disappointment for Psilocybin Advocates, but Progressive Policy May Still be on the Horizon"},"content":{"rendered":"

A three-judge panel of the U.S. Court of Appeals for the Ninth Circuit dismissed a petition for review of a Drug Enforcement Administration (DEA) response to an attorney\u2019s letter seeking advice and guidance on how a physician could administer psilocybin to a terminally ill patient without incurring liability under the Controlled Substances Act (CSA). Despite Petitioners\u2019 noble cause, the case turned on a technicality after the Court determined that the DEA\u2019s letter stating that such psilocybin treatment was not allowed, the document that prompted the lawsuit, was not a \u201cfinal\u201d decision of the Attorney General that the Court had jurisdiction to review.<\/p>\n

Background<\/h3>\n

a. Psilocybin<\/strong><\/h4>\n

Psilocybin is the hallucinogenic chemical found in \u201cmagic mushrooms.\u201d Controlled research into psilocybin for therapeutic purposes reveals that it may allow people suffering from depression, anxiety, PTSD, and potentially addiction, to more easily face and overcome painful or stressful memories and experiences. Psilocybin\u2019s therapeutic benefits are so promising that Denver, Colorado became the first city to decriminalize psilocybin in May 2019, and in 2020, Oregon passed Measure 109, which paved the road for a program allowing for legal manufacture, delivery, and administration of psilocybin to clients at supervised, licensed facilities in the state.<\/p>\n

Oregon isn\u2019t alone; legislators in New York and Washington State also recently introduced bills to legalize supervised psilocybin services in those states. While some states recognize its positive uses and have legalized supervised use at the state level, psilocybin is still federally illegal because it is currently registered as a Schedule I drug under the CSA. This means it can be produced, dispensed, or possessed only in the context of research, which requires special registration, the requirements of which the DEA is responsible for enforcing. Enter the Right to Try (RTT) Act.<\/p>\n

b. The RTT Act<\/strong><\/h4>\n

Congress passed the RTT Act in 2018 to give qualifying patients access to investigational drugs outside of a clinical trial setting. This effectively relieved regulatory requirements that would otherwise be imposed on eligible investigational drugs, speeding up the timeline for giving dying patients the \u201cright to try\u201d a drug that could potentially alleviate anxiety and depression associated with terminal illness and palliative care.<\/p>\n

To qualify under the Act, a drug or treatment must: 1) have completed an FDA-approved Phase 1 clinical trial; 2) be in an active clinical trial intended to form the basis of an application for approval or be the subject of an application for approval filed with the FDA; and 3) be in ongoing active development or production and not discontinued by the manufacturer or placed on clinical hold.<\/p>\n

Psilocybin successfully completed an FDA-approved Phase 1 clinical trial in 2019, and two companies, COMPASS Pathways and Usona, both currently have Phase 2 trials ongoing. Thus, psilocybin would appear to fit squarely within the RTT Act\u2019s definition of qualifying drugs. The issue in question that formed the basis of the lawsuit was how psilocybin could be dispensed to cancer patients under the RTT Act without violating the CSA.<\/p>\n

Case Context<\/h3>\n

The lawsuit\u2019s origins take place on a simple timeline. In January 2021, Dr. Sunil Aggarwal, co-director of the Advanced Integrative Medical Science Institute (AIMS) in Seattle, Washington, and Kathryn Tucker, counsel to AIMS and Mr. Aggarwal, wrote a letter to the DEA Regulatory Section. The letter requested advice from the DEA on how Dr. Aggarwal could obtain and administer psilocybin for therapeutic use with terminally ill cancer patients suffering anxiety and depression. After the initial letter, Ms. Tucker also sent an additional email to the DEA suggesting that the DEA could also simply issue Dr. Aggarwal an exemption from prosecution under the CSA via the RTT Act (the DEA has previously issued exemptions for religious purposes\u2014click here for more information).<\/p>\n

One week later, Thomas Prevoznik, Deputy Assistant Administrator, Diversion Control Division of the DEA responded to Dr. Aggarwal\u2019s letter. The DEA response stated that, \u201cthe RTT does not waive the requirements of any provision of the CSA or its implementing regulations,\u201d and \u201cabsent an explicit statutory exemption to the CSA, DEA has no authority to waive any of the CSA\u2019s requirements pursuant to the RTT.\u201d The DEA confirmed that Dr. Aggarwal could apply for researcher registration but rejected the idea of issuing an exemption from prosecution because that specific provision \u201capplies to individuals already registered with DEA to engage in research in controlled substances,\u201d and Dr. Aggarwal did not have registration for researching psilocybin. The response concluded that if Dr. Aggarwal obtained researcher registration from the DEA, then he could petition the DEA Administrator for a grant of exemption from prosecution under the CSA.<\/p>\n

Petition for Review<\/h3>\n

In response to the DEA\u2019s letter, AIMS, Dr. Aggarwal, and two patients seeking access to psilocybin under the RTT Act filed a lawsuit in the U.S. Circuit Court of Appeals for the Ninth Circuit pursuant to 21 U.S.C. \u00a7 877, a provision allowing judicial review of final decisions of the Attorney General. It was in the language of this statute that Petitioners\u2019 case ultimately failed.<\/p>\n

Although the term \u201cfinal\u201d is not defined in the statute, legal precedent, stemming mainly from Bennett v. Spear, 520 U.S. 154, 177-78 (1997), established a two-part test for determining whether an administrative action is a \u201cfinal\u201d decision: 1) the action must mark the consummation of the agency\u2019s decision-making process and must not be of merely tentative or interlocutory nature, and 2) the action must be one by which rights or obligations have been determined or from which legal consequences will flow. Ultimately, an administrative agency\u2019s decision is final \u201cwhen the agency has rendered its last word on the matter in question.\u201d<\/p>\n

The panel for the Ninth Circuit determined that the DEA\u2019s response was not a \u201cfinal\u201d decision under the meaning of Bennett, and because of this, the Court lacked jurisdiction to hear the case, necessarily requiring the panel to dismiss the action. The Court distinguished between an informational document providing an agency\u2019s interpretation of a statute (not considered final agency action) and a decision that determines how a statute or regulation applies to facts for enforcement purposes. The Court deemed the DEA\u2019s response an informational letter, the type of advice letter that agencies prepare countless times per year in dealing with a regulated community.<\/p>\n

Using Bennett specifically, the Court found that the DEA\u2019s response failed both required elements to be considered \u201cfinal.\u201d First, regarding consummation of a fact-finding process, the Court found no indication that the DEA\u2019s response was preceded by fact-finding or a public hearing, or that the DEA engaged in a decision-making process that resulted in the letter. The DEA\u2019s response simply informed Ms. Tucker that the RTT Act on its face did not give the DEA authority to waive CSA requirements and did not grant or deny any request or make any ultimate decision.<\/p>\n

Regarding Bennett\u2019s second element requiring imposition of legal consequences, the Court found that the DEA\u2019s response did nothing but point to the plain language of existing law and failed to expressly impose any legal consequences for noncompliance. The panel noted that if Dr. Aggarwal chose to ignore the DEA\u2019s response and offered psilocybin to his patients, he would face liability only for noncompliance with the CSA, not for disagreeing with the agency\u2019s determination stated in its response. Thus, because the letter\u2019s content was not the consummation of a fact-finding process and failed to impose any form of legal consequences, the Court found the letter did not suffice as \u201cfinal,\u201d as required for judicial review under \u00a7 877.<\/p>\n

To contrast its decision with prior cases, the Court gave examples of responses and documents that were ultimately deemed final. First, in Hemp Indus. Ass\u2019n v. DEA, 333 F.3d 1082, 1085 (9th Cir. 2003), the DEA published a rule that banned the sale of certain products containing hemp products in the Federal Register. The Court deemed that rule final because it imposed obligations and sanctions in the event of violation. Similarly, in John Doe, Inc. v. DEA, 484 F.3d 561, 566 (D.C. Cir. 2007), the D.C. Circuit found that it had jurisdiction under \u00a7 877 to review the DEA\u2019s denial of a permit application. The Court deemed the decision final because the DEA affirmatively denied the permit application, thus marking the culmination of its decision-making process and establishing legal consequences by expressly prohibiting action without a permit.<\/p>\n

BOTTOM LINE<\/h3>\n

Although the Ninth Circuit\u2019s opinion is disappointing for RTT advocates and psychedelics proponents, remember that the Court dismissed the case on a relative technicality, rather than the merits. This case had strong support across the country\u2014last spring, a bipartisan group of attorneys general from eight states and the District of Columbia, along with the ACLU, and both the Cato and Goldwater institutes submitted amicus briefs supporting Petitioners and noting psilocybin\u2019s therapeutic properties. A coalition of end-of-life caretakers and a group of law professors and bioethicists also submitted briefs supporting Petitioners\u2019 case. Further, just last month, a bipartisan group of Congress members sent a letter urging the DEA to give terminally ill patients access to psilocybin. In conclusion, despite the Court\u2019s decision in this case, it is our opinion that the advocates bringing this case are tireless and committed and are likely even now digesting this decision and preparing to redouble their efforts in order to obtain a decision on the merits on this important issue.<\/p>\n

Note: This post originally appeared on the Green Light Law Group Blog.<\/p>\n","protected":false},"excerpt":{"rendered":"

A three-judge panel of the U.S. Court of Appeals for the Ninth Circuit dismissed a petition for review of a Drug Enforcement Administration (DEA) response to an attorney\u2019s letter seeking advice and guidance on how a physician could administer psilocybin to a terminally ill patient without incurring liability under the Controlled Substances Act (CSA). Despite […]<\/p>\n","protected":false},"author":6,"featured_media":1619,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[28],"tags":[37,40,41],"class_list":["post-1618","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-legal-cannabis-blog","tag-legislation","tag-oregon","tag-psychedelics"],"yoast_head":"\nAIMS v. 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